Skin that Looks Hydrated, from the Inside Out

HA, PN and PDRN Skin Boosters at MediFresh — for skin that glows, holds moisture, and feels healthier long-term.

Some concerns aren't about lines or volume. They're about the quality of your skin — the dullness that no serum seems to fix, the dryness that persists no matter how much you drink, the loss of that natural glow you used to have. Skin boosters work beneath the surface to restore what your skin needs to look and feel its best.

What You Can Expect

Within a few weeks of your first session, you'll notice your skin holding moisture differently. It looks less dull. Fine surface lines appear softer. Your skin has a natural radiance — not from product sitting on top of it, but from within. A series of treatments delivers the best results, with ongoing improvement that builds over time.

Three Options, One Goal

Hyaluronic Acid (HA) Skin Boosters

HA skin boosters deliver ultrafine hyaluronic acid directly into the dermis — the layer of skin responsible for hydration and elasticity. Unlike traditional filler, this isn't about adding volume or changing structure. It's about rehydrating and plumping the skin at a cellular level so it functions better.
Best for: Dehydrated skin, fine surface lines, loss of radiance, skin that feels rough or dull Results: Gradual improvement over 2–4 weeks; a series of 2–3 sessions is typically recommended for optimal results

Polynucleotide (PN) Skin Boosters

PN skin boosters use long-chain DNA fragments — derived from salmon — with a high molecular weight (1,260–1,570 kDa) that form a stable, three-dimensional scaffold within the dermis. Rather than simply signaling repair, PN physically restructures the extracellular matrix, stimulating fibroblasts to produce more collagen, elastin, and hyaluronic acid from within.

The result is deeper, more sustained skin remodeling — firmer, denser skin with improved texture, tone, and resilience that builds over a series of treatments.

Best for: Anti-aging, structural skin remodeling, chronic photodamage, skin laxity, and uneven texture. Ideal for clients wanting long-lasting results with fewer maintenance visits. Results: Builds progressively over a series; most clients see significant improvement by session 3

PDRN Skin Boosters

PDRN skin boosters use short-chain DNA fragments — derived from salmon — with a lower molecular weight that penetrates quickly and activates adenosine receptors in fibroblasts. This triggers a cascade that reduces inflammation, accelerates cell proliferation, and supports faster tissue repair.

The result is skin that recovers and regenerates more quickly — with reduced redness, improved hydration, and a refreshed appearance that becomes visible sooner in the treatment series.

Best for: Post-procedure recovery, reactive or sensitive skin, and as an add-on to treatments like microneedling or laser. Ideal for clients wanting faster visible results or combining with other services. Results: Builds progressively over a series; most clients see significant improvement by session 3

Our Approach

An Injector will assess your skin and recommend whether HA or PDRN is the right starting point — or whether a combination approach serves your goals better. There's no one-size answer here. Your skin history, concerns, and goals shape every recommendation.

What You can Expect at Your Visit